Procurement of a new DBS system that shall contribute to maintaining a treatment alternative for advanced Parkinsons disease, which has been offered at St. Olavs Hospital HF since 2001. During DBS surgery, micro electrode recordings and test simulation of deep structures in the brain are carried out in order to optimise the correct placement of the last electrode in accordance with the gold standard in the field. The DBS system that is currently used in Trondheim is now more than 10 years old and it needs to be replaced. The new system must allow secure, practical, efficient and precise micro electrode recordings and test simulation for standard DBS surgical procedure, with sufficient visualisation and logging of the procedure.
The new DBS system shall also be used to collect neurophysiological data for research. Therefore, the new system must be capable of recording the signals that are available through clinical procedure with high enough quality and precision that it can be informative scientifically. This means that there are additional requirements to the system beyond those that are necessary for clinical procedures and many clinical systems have limitations as regards sufficient capture of this valuable data. In order to allow an intra-operative experiment protocol with minimal interference with surgical procedures, the system must have flexible settings that enables data to be registered and visualised in accordance with both clinical and scientific needs and to allow an even transition between the clinical procedure and and research protocol. The data must have a good signal-to-noise-relationship, it must be continually recorded, with a high sampling speed and flexible settings for frequency filters and referrals, so that both spiking activity and local field potentials can be recorded from all relevant contacts. The system must have a sufficient number of suitable recording channels in order to allow simultaneous recordings from all electrodes in use and also from several relevant sensors such movement sensors or EEG channels. Finally, the system must allow secure and precise access to a digital pulse from a behaviour testing mobile machine, which will allow high precision synchronisation between intra-operative tested behaviour and the registered signal. Advanced simulation settings and the option to play during a simulation will also enable clinical and scientific evaluations of the effect of the simulation.
For further system requirements, please see the technical specifications in annex 1 (see the annex).